Peptides are a compound that consist of two or more amino acids, linked together in a chain. Amino acids already naturally exist in all living organisms and are responsible for creating a number of biological responses. At Paradigm Research Products, we provide peptides, artificially created, that act as catalysts to replicate or trigger certain chemical processes.

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Induced splice modulation of pre-mRNAs shows promise to correct aberrant disease transcripts and restore functional protein and thus has therapeutic potential. Duchenne muscular dystrophy (DMD) results from mutations that disrupt the DMD gene open reading frame causing an absence of dystrophin protein. Antisense oligonucleotide (AO)-mediated exon skipping has been shown to restore functional dystrophin in mdx mice and DMD patients treated intramuscularly in two recent phase 1 clinical trials. Critical to the therapeutic success of AO-based treatment will be the ability to deliver AOs systemically to all affected tissues including the heart. Here, we report identification of a series of transduction peptides (Pip5) as AO conjugates for enhanced systemic and particularly cardiac delivery. One of the lead peptide-AO conjugates, Pip5e-AO, showed highly efficient exon skipping and dystrophin production in mdx mice with complete correction of the aberrant DMD transcript in heart, leading to >50% of the normal level of dystrophin in heart. Mechanistic studies indicated that the enhanced activity of Pip5e-phosphorodiamidate morpholino (PMO) is partly explained by more efficient nuclear delivery. Pip5 series derivatives therefore have significant potential for advancing the development of exon skipping therapies for DMD and may have application for enhanced cardiac delivery of other biotherapeutics.
An additional quick note is to assure you are entirely truthful when you sign up for peptides. If you have not been forthcoming relating to various other medications as well as wellness issues – after that we can’t establish your threat element. Be straightforward as well as you should not have any type of dramatization with peptide adverse effects.

Peptides are a compound that consist of two or more amino acids, linked together in a chain. Amino acids already naturally exist in all living organisms and are responsible for creating a number of biological responses. At Paradigm Research Products, we provide peptides, artificially created, that act as catalysts to replicate or trigger certain chemical processes.


Other peptides amplify the body’s response to its own testosterone site-specifically within muscle and bone only. Steroids, on the other hand, produce their highly desired anabolic effects by acting on these receptors, but also come coupled with the less-sought-after side effects of acne, oily skin, hair loss, aggression, breast enlargement and testicular shrinkage. It is for this reason, these amino acid chains are serving as an increasingly popular alternative to steroids amongst aesthetic gym goers, providing many of the anabolic effects without the unwanted side effect profile.
There are a lot of reputable peptides companies in Australia, who supply high quality peptides to help get your life on track. With strict laws involved in selling peptides, it is essential you find a company who complies with them. Recent years have seen many companies worldwide having to close due to strict laws.  We suggest you do your research and use a company that offers high quality, genuine and safe products. Ensure you read carefully what the company offers. Don’t go for the cheapest, they may not be pure.
Peptides possess a host of benefits but there are some disadvantages. First of all, they are a little more expensive than most supplements. That’s because they contain complex chemicals that work efficiently – more efficiently than many other health supplements on the market. They can also come with a few minor side effects such as dry mouth, increased hunger and water retention.
Peptides Direct are an Australian based retailer in research peptides. Operating out of their main office in Queensland this company have a reputation to be proud of. The quality of their products as well as the helpful and professional advise that’s available from their own in house doctor makes Peptides Direct a unique force and this is what keeps them as a major competitor in their field.
Often when something is too good to be true, it usually is. The reality is peptides are not a magic potion that substitutes good nutrition, exercise and lifestyle choices. Fundamentally, peptides enhance the body’s own natural processes to produce their various effects, and many of these protein chains are already produced in the body to a certain degree. Often referred to as “the fountain of youth”, certain peptides have shown to reverse the decline in metabolic processes and repair associated with aging, restoring the body back into a more regenerative, youthful state by stimulating release of the body’s own natural human growth hormone (hGH).
Another point worth mentioning is that several Australian’s have chosen the cheaper route, and that is the decision to order from the United States. Please note that although one can source some top quality products this way, many have faced great disappointment. This has been at the mercy of the Customs office of Australia and they will cease such items at once.
However, it cannot be legally imported without a special permit under the strict Special Access Scheme, which requires a doctor to apply to the TGA for permission to treat a particular patient with the drug, including describing the specific clinical need. ''There have been no applications under the SAS for AOD-9604,'' the TGA spokeswoman confirmed on Thursday.
The peptides suppliers in Australia should all comply with the above, however it is very important for each individual to check this with the chosen peptide supplier. You must avoid at all cost the temptation of buying any research chemicals from a firm that is prepared to provide them without a prior medical evaluation. It’s your choice, but be warned as fake or diluted peptides can prove fatal! A good tip here is to check out a good peptide clinics review.
Whilst we have seen amazing results from this treatment, please know that results vary and we cannot make guarantees. We recommend coming and speaking to our registered nurses for an in-depth consultation. They will discuss in detail how the treatment works, whether it will be right for your skin type and the expected results in line with your skin goals.
In the current times, it is rather important for every company to have a website of its own since this is the first criterion on which prospective clients would judge you. The website of Peptides Direct is a little different to its competitors. To browse its site, you would first have to register on it. However, this is not a big deal because you would be required to register at all places before ordering.
We at Muscle Peptides Australia specialise in providing customers with the highest quality peptide supplements that can enable them to unlock their body’s full potential. Operating out of Melbourne and headed by a team of experienced anti-ageing doctors, we offer our customers a no-obligation online assessment. Customers can make enquiries by e-mailing info@musclepeptides.com.au and have their questions answered by the company’s doctor, you can request information about everything from supplements to fitness, muscle building, anti-aging and weight loss.
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